ea0015p177 | Endocrine tumours and neoplasia | SFEBES2008
Dixit Kashinath
, Shablak Alaaeldin
, Jacob Koshy
, Walmsley David
, Hawkins Robert
, Trainer Peter
Adrenocortical carcinoma are rare, highly vascular tumours with a generally poor prognosis. We have studied the use of the antiangiogenic drug, thalidomide (TH), in 6 patients with metastatic adrenocortical carcinoma (5 patients had adrenalectomy and one patient was inoperable#). The response to thalidomide treatment is summarized in the following Table. Assuming the residual/metastatic tumours to have a spheroidal form, the tumour volume (V) was calculated using the eq...